Cloned (Comment) | Organism |
---|---|
expression of cDNA in Escherichia coli | Homo sapiens |
expression of cDNA in Escherichia coli | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.2 | - |
glutathione | - |
Homo sapiens | |
0.2 | - |
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | - |
Homo sapiens | |
0.2 | - |
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | - |
Rattus norvegicus | |
0.3 | - |
glutathione | - |
Rattus norvegicus | |
0.3 | - |
glutathione | glutathione S-transferase activity | Rattus norvegicus | |
3.2 | - |
1-chloro-2,4-dinitrobenzene | - |
Homo sapiens | |
5 | - |
1-chloro-2,4-dinitrobenzene | - |
Rattus norvegicus | |
8 | - |
glutathione | glutathione S-transferase activity | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
23000 | - |
x * 23000, SDS-PAGE | Homo sapiens |
23000 | - |
x * 23000, SDS-PAGE | Rattus norvegicus |
23298 | - |
x * 23298, deduced from nucleotide sequence | Rattus norvegicus |
23359 | - |
x * 23359, deduced from nucleotide sequence | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | Homo sapiens | - |
(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate | - |
? | |
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | Rattus norvegicus | - |
(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate | - |
? | |
1-bromo-2,4-dinitrobenzene + glutathione | Homo sapiens | - |
? | - |
? | |
1-bromo-2,4-dinitrobenzene + glutathione | Rattus norvegicus | - |
? | - |
? | |
1-chloro-2,4-dinitrobenzene + glutathione | Homo sapiens | - |
? | - |
? | |
1-chloro-2,4-dinitrobenzene + glutathione | Rattus norvegicus | - |
? | - |
? | |
1-fluoro-2,4-dinitrobenzene + glutathione | Homo sapiens | - |
? | - |
? | |
1-fluoro-2,4-dinitrobenzene + glutathione | Rattus norvegicus | - |
? | - |
? | |
1-iodo-2,4-dinitrobenzene + glutathione | Homo sapiens | - |
? | - |
? | |
1-iodo-2,4-dinitrobenzene + glutathione | Rattus norvegicus | - |
? | - |
? | |
allyl isothiocyanate + glutathione | Homo sapiens | - |
? | - |
? | |
allyl isothiocyanate + glutathione | Rattus norvegicus | - |
? | - |
? | |
benzyl isothiocyanate + glutathione | Homo sapiens | - |
? | - |
? | |
benzyl isothiocyanate + glutathione | Rattus norvegicus | - |
? | - |
? | |
cumene hydroperoxide + 2 GSH | Homo sapiens | - |
cumene hydroxide + GSSG + H2O | - |
? | |
cumene hydroperoxide + 2 GSH | Rattus norvegicus | - |
cumene hydroxide + GSSG + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | O35543 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant PGDS | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | - |
Homo sapiens | (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate | - |
? | |
(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13-dienoate | - |
Rattus norvegicus | (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate | - |
? | |
1-bromo-2,4-dinitrobenzene + glutathione | - |
Homo sapiens | ? | - |
? | |
1-bromo-2,4-dinitrobenzene + glutathione | - |
Rattus norvegicus | ? | - |
? | |
1-chloro-2,4-dinitrobenzene + glutathione | - |
Homo sapiens | ? | - |
? | |
1-chloro-2,4-dinitrobenzene + glutathione | - |
Rattus norvegicus | ? | - |
? | |
1-fluoro-2,4-dinitrobenzene + glutathione | - |
Homo sapiens | ? | - |
? | |
1-fluoro-2,4-dinitrobenzene + glutathione | - |
Rattus norvegicus | ? | - |
? | |
1-iodo-2,4-dinitrobenzene + glutathione | - |
Homo sapiens | ? | - |
? | |
1-iodo-2,4-dinitrobenzene + glutathione | - |
Rattus norvegicus | ? | - |
? | |
allyl isothiocyanate + glutathione | - |
Homo sapiens | ? | - |
? | |
allyl isothiocyanate + glutathione | - |
Rattus norvegicus | ? | - |
? | |
benzyl isothiocyanate + glutathione | - |
Homo sapiens | ? | - |
? | |
benzyl isothiocyanate + glutathione | - |
Rattus norvegicus | ? | - |
? | |
cumene hydroperoxide + 2 GSH | - |
Homo sapiens | cumene hydroxide + GSSG + H2O | - |
? | |
cumene hydroperoxide + 2 GSH | - |
Rattus norvegicus | cumene hydroxide + GSSG + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 23000, SDS-PAGE | Homo sapiens |
? | x * 23000, SDS-PAGE | Rattus norvegicus |
? | x * 23298, deduced from nucleotide sequence | Rattus norvegicus |
? | x * 23359, deduced from nucleotide sequence | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
glutathione-dependent prostaglandin D2 synthase | - |
Homo sapiens |
glutathione-dependent prostaglandin D2 synthase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
glutathione | - |
Homo sapiens | |
glutathione | - |
Rattus norvegicus |