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Literature summary for 5.3.4.1 extracted from
- Lumen size matters role of protein disulfide isomerase A1 in vascular remodeling (2016), Hypertension, 67, 488-489 .
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Homo sapiens | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDIA1 | - |
Homo sapiens |
| protein disulfide isomerase A1 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | enzyme inhibition results ina 25% loss of vessel caliber post-injury. This is accompanied by decreased hydrogen peroxide formation and changes in collagen organization, resulting in increased arterial stiffness | Homo sapiens |
| physiological function | the enzyme is a regulatorof vessel architecture and circumference that prevents inward remodeling without effects on wall thickness or neointima formation | Homo sapiens |
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Release 2023.1 (January 2023)
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