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Literature summary for 5.3.4.1 extracted from

  • Soares Moretti, A.I.; Martins Laurindo, F.R.
    Protein disulfide isomerases Redox connections in and out of the endoplasmic reticulum (2017), Arch. Biochem. Biophys., 617, 106-119 .
    View publication on PubMed
Search for more literature for 5.3.4.1

Inhibitors

Inhibitors Comment Organism Structure
CCF642
-
 Homo sapiens
LOC14
-
 Homo sapiens
quercetin-3-rutinoside
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-actin Homo sapiens
-
 ?
-
 ?
integrin alphaIIbbeta3 Homo sapiens
-
 ?
-
 ?
integrin alphaMb2 Homo sapiens
-
 ?
-
 ?
integrin alphaVb3 Homo sapiens
-
 ?
-
 ?
integrin alphaVbeta3 Homo sapiens
-
 ?
-
 ?
tissue factor Homo sapiens
-
 ?
-
 ?
transforming growth factor-beta1 Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-actin
-
 Homo sapiens ?
-
 ?
integrin alphaIIbbeta3
-
 Homo sapiens ?
-
 ?
integrin alphaMb2
-
 Homo sapiens ?
-
 ?
integrin alphaVb3
-
 Homo sapiens ?
-
 ?
integrin alphaVbeta3
-
 Homo sapiens ?
-
 ?
tissue factor
-
 Homo sapiens ?
-
 ?
transforming growth factor-beta1
-
 Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 55000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
PDIA1
-
 Homo sapiens
protein disulfide isomerase
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function isoform PDIA1 is required for agonist-triggered Nox NADPH oxidase activation and cell migration in vascular cells and macrophages. The enzyme also plays role in cytoskeleton organization Homo sapiens