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Literature summary for 5.3.4.1 extracted from
- Enhancement of the activity of renatured lysozyme by protein disulfide isomerase (2007), J. Biosci. Bioeng., 104, 235-237.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| overexpression in Bacillus brevis, secretion to the cell medium | Humicola insolens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | refolding reaction obeys almost first-order kinetics with respect to PDI concentration | Humicola insolens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Humicola insolens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| denatured lysozyme | PDI catalyzes the formation, rearrangement, and breakage of disulfide bonds, oxidative refolding by PDI almost completely restores lysozyme activity, overview | Humicola insolens | ? | - |
? |  |
| additional information | PDI also functions as a dehydroascorbate reductase and a molecular chaperone besides its disulfide-isomerizing function | Humicola insolens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PDI | - |
Humicola insolens |
| protein disulfide isomerase | - |
Humicola insolens |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 22 | - |
assay at room temprature | Humicola insolens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| GSH | - |
Humicola insolens | |
| GSSG | - |
Humicola insolens | |
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Release 2023.1 (January 2023)
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