Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bacitracin | - |
Homo sapiens | |
additional information | inhibition by PDI-specific antibodiy RL90 | Homo sapiens | |
Phenylarsine oxide | complete inhibition at 0.01-0.1 mM in vivo | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme mediates rapid delivery of NO signalling into human platelets from the S-nitrosothiol compound S-nitrosoglutathione, NO delivery is blocked by inhibition of PDI, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme mediates rapid delivery of NO signalling into human platelets from the S-nitrosothiol compound S-nitrosoglutathione, NO delivery is blocked by inhibition of PDI, overview | Homo sapiens | ? | - |
? | |
additional information | the enzyme shows disulfide exchange activity | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PDI | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
in vivo assay at | Homo sapiens |