Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 5.3.4.1 extracted from

  • Klappa, P.; Koivunen, P.; Pirneskoski, A.; Karvonen, P.; Ruddock, L.W.; Kivirikko, K.I.; Freedman, R.B.
    Mutations that destabilize the a' domain of human protein-disulfide isomerase indirectly affect peptide binding (2000), J. Biol. Chem., 275, 13213-13218.
    View publication on PubMed
Search for more literature for 5.3.4.1

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli and Sf9 insect cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
F449W no DELTA-somatostatin binding Homo sapiens
F449Y binds DELTA-somatostatin like wild-type Homo sapiens
F454A binds DELTA-somatostatin like wild-type Homo sapiens
G448R binds DELTA-somatostatin like wild-type Homo sapiens
K450A binds DELTA-somatostatin like wild-type Homo sapiens
L453E no DELTA-somatostatin binding Homo sapiens
R444A binds DELTA-somatostatin like wild-type Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Homo sapiens 5783
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant PDI Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
unfolded disulfide-bonded protein
-
 Homo sapiens refolded disulfide-bonded protein
-
 ?