Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.005 | - |
insulin-(SS) | - |
Rattus norvegicus | |
17 | - |
GSH | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55114 | - |
x * 55114, calculation from nucleotide sequence | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bos taurus | - |
? | - |
? | |
additional information | Mammalia | protein disulfide isomerase serves as a subunit of at least two enzymes, the beta-subunit of the enzyme prolyl hydroxylase and an ER triglyceride transferase | ? | - |
? | |
Proteins | Rattus norvegicus | - |
? | - |
? | |
Proteins | Bos taurus | - |
? | - |
? | |
Proteins | Mammalia | when present in large stoichiometric excess relative to an unfolded protein substrate, the enzyme can exhibit chaperone activity, inhibiting aggregation and increasing the recovery of native protein | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Mammalia | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Saccharomyces cerevisiae |
glycoprotein | - |
Bos taurus |
no glycoprotein | - |
Rattus norvegicus |
no glycoprotein | - |
Bos taurus |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Insulin-(SS) + GSH | - |
Rattus norvegicus | Insulin-(SH)2 + GSSG | - |
? | |
Insulin-(SS) + GSH | - |
Bos taurus | Insulin-(SH)2 + GSSG | - |
? | |
additional information | - |
Bos taurus | ? | - |
? | |
additional information | protein disulfide isomerase serves as a subunit of at least two enzymes, the beta-subunit of the enzyme prolyl hydroxylase and an ER triglyceride transferase | Mammalia | ? | - |
? | |
Proteins | native, reduced or with wrong disulfide bonds | Mammalia | Proteins | with correct disulfide bonds | ? | |
Proteins | native, reduced or with wrong disulfide bonds | Rattus norvegicus | Proteins | with correct disulfide bonds | ? | |
Proteins | native, reduced or with wrong disulfide bonds | Saccharomyces cerevisiae | Proteins | with correct disulfide bonds | ? | |
Proteins | native, reduced or with wrong disulfide bonds | Bos taurus | Proteins | with correct disulfide bonds | ? | |
Proteins | incorrectly disulfide-linked RNAse | Rattus norvegicus | Proteins | with correct disulfide bonds | ? | |
Proteins | - |
Rattus norvegicus | ? | - |
? | |
Proteins | - |
Bos taurus | ? | - |
? | |
Proteins | when present in large stoichiometric excess relative to an unfolded protein substrate, the enzyme can exhibit chaperone activity, inhibiting aggregation and increasing the recovery of native protein | Mammalia | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | - |
Bos taurus |
? | x * 55114, calculation from nucleotide sequence | Rattus norvegicus |