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Literature summary for 5.3.3.8 extracted from
- DELTA3-cis,DELTA2-trans-Enoyl-CoA isomerase from rat liver mitochondria (1979), Methods Enzymol., 14, 99-105.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| long-chain acyl-CoA thioesters | - |
Rattus norvegicus |  |
| Medium-chain acyl-CoA thioesters | - |
Rattus norvegicus | |
| PCMB | 0.5 mM, 50% inhibition | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no requirement for metal ions | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | involved in the enzymatic degradation of the cis-olefinic system of monounsaturated and polyunsaturated fatty acids | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, stable for more than 3 years | Rattus norvegicus |
| 0-4°C, slow loss of activity | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | no specificity for DELTA3-cis-enoyl-CoA esters of chain length between C6 and C16 | Rattus norvegicus | ? | - |
? | |
| additional information | involved in the enzymatic degradation of the cis-olefinic system of monounsaturated and polyunsaturated fatty acids | Rattus norvegicus | ? | - |
? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
- |
4 | slow loss of activity | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 9 | - |
Rattus norvegicus |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.5 | - |
PCMB | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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