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Literature summary for 5.3.3.2 extracted from

  • Hahn, F.M.; Xuan, J.W.; Chambers, A.F.; Poulter, C.D.
    Human isopentenyl diphosphate:dimethylallyl diphosphate isomerase: overproduction, purification, and characterization (1996), Arch. Biochem. Biophys., 332, 30-34.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
overexpressed in Escherichia coli Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.033
-
isopentenyl diphosphate
-
Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ Mn2+ or Mg2+ required Homo sapiens
Mg2+ maximal activation at 20 mM Homo sapiens
Mn2+ Mn2+ or Mg2+ required Homo sapiens
Mn2+ maximal activation at 0.1 mM Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Isopentenyl diphosphate Homo sapiens essential activation step in isoprenoid biosynthetic pathway ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
isopentenyl diphosphate
-
Homo sapiens dimethylallyl diphosphate
-
?
Isopentenyl diphosphate essential activation step in isoprenoid biosynthetic pathway Homo sapiens ?
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
in presence of Mg2+ Homo sapiens