Literature summary for 5.3.3.2 extracted from

Sagami, H.; Ogura, K.
Multiple forms of isopentenyl pyrophosphate isomerase of avian liver (1983), J. Biochem., 94, 975-979.

Search for more literature for 5.3.3.2

Activating Compound

Activating Compound	Comment	Organism	Structure
2-mercaptoethanol	activates isomerase III and IV	Gallus gallus

Inhibitors

Inhibitors	Comment	Organism	Structure
diphosphate	inhibitory effect decreases in the order of isomerases I, II, III, and IV	Gallus gallus
iodoacetamide	inhibitory effect decreases in the order of isomerases I, II, III, no inhibition of isomerase IV	Gallus gallus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0013	-	isopentenyl diphosphate	isomerase II and III	Gallus gallus
0.0017	-	isopentenyl diphosphate	isomerase I	Gallus gallus
0.0025	-	isopentenyl diphosphate	isomerase IV	Gallus gallus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Co2+	slight activation	Gallus gallus
Mg2+	slight activation	Gallus gallus
Mn2+	isomerase I: maximal activation at 0.5 mM, isomerase II, III or IV: maximal activation at 0.25 mM	Gallus gallus
Ni2+	slight activation	Gallus gallus

Organism

Organism	UniProt	Comment	Textmining
Gallus gallus	-	4 enzyme forms: I, II, III, and IV	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Gallus gallus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
isopentenyl diphosphate	-	Gallus gallus	dimethylallyl diphosphate	-	?

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
6.6	-	-	Gallus gallus

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Release 2023.1 (January 2023)