Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2-mercaptoethanol | activates | Sus scrofa | |
dithiothreitol | activates | Sus scrofa | |
glutathione | activates | Sus scrofa | |
L-Cysteine hydrochloride | activates | Sus scrofa | |
mevalonic acid | activates | Sus scrofa | |
Mevalonic acid lactone | weakly activates | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(+/-)-cis/trans-Chrysanthemyl diphosphate | - |
Sus scrofa | |
(+/-)-cis/trans-Chrysanthemyl monophosphate | - |
Sus scrofa | |
2,2-Diphenyl-1-(beta-dimethylaminoethoxy)pentane hydrochloride | - |
Sus scrofa | |
ATP | partial | Sus scrofa | |
beta-Diethylaminoethyldiphenylpropylacetate hydrochloride | i.e. SKF-525A | Sus scrofa | |
geranyl diphosphate | - |
Sus scrofa | |
geranyl monophosphate | - |
Sus scrofa | |
iodoacetamide | - |
Sus scrofa | |
iodoacetic acid | - |
Sus scrofa | |
KH2PO4 | - |
Sus scrofa | |
linaloyl diphosphate | - |
Sus scrofa | |
linaloyl monophosphate | - |
Sus scrofa | |
NEM | - |
Sus scrofa | |
neryl diphosphate | - |
Sus scrofa | |
Neryl monophosphate | - |
Sus scrofa | |
p-hydroxymercuribenzoate | - |
Sus scrofa | |
Sodium acetate | - |
Sus scrofa | |
Terpene diphosphate esters | - |
Sus scrofa | |
Terpene monophosphate esters | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0027 | - |
isopentenyl diphosphate | - |
Sus scrofa |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | restores activity after EDTA treatment | Sus scrofa | |
Mg2+ | maximal activation at 5 mM | Sus scrofa | |
Mn2+ | restores activity after EDTA treatment | Sus scrofa | |
Mn2+ | maximal activation at 2 mM, activity maximum obtained with Mn2+ is about 3times that with Mg2+ | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
82500 | - |
gel filtration | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
5.92 | - |
- |
Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
isopentenyl diphosphate | - |
Sus scrofa | dimethylallyl diphosphate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.3 | - |
- |
Sus scrofa |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.5 | 7.5 | pH 5.5: about 35% of maximal activity, pH 7.5: about 30% of maximal activity | Sus scrofa |