Literature summary for 5.3.3.14 extracted from

Endo, K.; Helmkamp, G.M.; Bloch, K.
Mode of inhibition of beta-hydroxydecanoyl thioester dehydrase by 3-decynoyl-N-acetylcysteamine (1970), J. Biol. Chem., 245, 4293-4296.

Inhibitors

Inhibitors	Comment	Organism	Structure
3-decynoyl-N-acetylcysteamine	irreversible inactivation of both dehydrase activity of EC 4.2.1.60 and isomerase activity of enzyme, inhibition occurs through isomerization to the allene and subsequent covalent modification of enzyme	Escherichia coli

Organism	UniProt	Comment	Textmining
Escherichia coli	-	multifunctional enzyme, catalyzing in addition reaction of EC 4.2.1.60	-

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Release 2023.1 (January 2023)