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Literature summary for 5.3.3.12 extracted from
- D-dopachrome tautomerase is over-expressed in pancreatic ductal adenocarcinoma and acts cooperatively with macrophage migration inhibitory factor to promote cancer growth (2016), Int. J. Cancer, 139, 2056-2067 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in HEK-293 cells | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-iodo-6-phenylpyrimidine | - |
Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| plasma membrane | - |
Homo sapiens | 5886 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| AsPC-1 cell | - |
Homo sapiens | - |
| BxPC-3 cell | - |
Homo sapiens | - |
| PANC-1 cell | - |
Homo sapiens | - |
| pancreatic ductal adenocarcinoma cell | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| D-dopachrome tautomerase | - |
Homo sapiens |
| DDT | - |
Homo sapiens |
| Mif-2 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | enzyme knockdown inhibits ERK1/2 and AKT phosphorylation, increases p53 expression and attenuates proliferation and invasion of PANC-1 cells | Homo sapiens |
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Release 2023.1 (January 2023)
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