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Literature summary for 5.3.3.12 extracted from

  • Hiyoshi, M.; Konishi, H.; Uemura, H.; Matsuzaki, H.; Tsukamoto, H.; Sugimoto, R.; Takeda, H.; Dakeshita, S.; Kitayama, A.; Takami, H.; Sawachika, F.; Kido, H.; Arisawa, K.
    D-Dopachrome tautomerase is a candidate for key proteins to protect the rat liver damaged by carbon tetrachloride (2009), Toxicology, 255, 6-14.
    View publication on PubMed
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus P80254 male Wistar rats
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Source Tissue

Source Tissue Comment Organism Textmining
liver
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 Rattus norvegicus
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Synonyms

Synonyms Comment Organism
D-dopachrome tautomerase
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 Rattus norvegicus
DDT
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 Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus carbon tetrachloride treatment of livers lead to a 12fold increased expression level of dopachrome tautomerase in male rats, proteomic analysis, overview. The increase in DDT is a response to liver damage, accelerates melanin biosynthesis and protects the liver from oxidative stress induced by CCl4 up

General Information

General Information Comment Organism
physiological function increase in D-dopachrome tautomerase is a response to liver damage, accelerates melanin biosynthesis and protects the liver from oxidative stress induced by CCl4, overview Rattus norvegicus