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Literature summary for 5.3.3.12 extracted from

  • Guyonneau, L.; Murisier, F.; Rossier, A.; Moulin, A.; Beermann, F.
    Melanocytes and pigmentation are affected in dopachrome tautomerase knockout mice (2004), Mol. Cell. Biol., 24, 3396-3403.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information enzyme knockout mutant, animals are viable and do not show any abnormalities in skin, retinal pigment epithelium, or brain. Animals show a diluted coat colour phenotype due to reduced melanin content in hair. Primary melanocytes from knockout animals are viable in culture and show a normal distribution of tyrosinase and tyrosinase-related protein 1 Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining