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Literature summary for 5.3.3.12 extracted from

  • Pak, B.J.; Lee, J.; Thai, B.L.; Fuchs, S.Y.; Shaked, Y.; Ronai, Z.; Kerbel, R.S.; Ben-David, Y.
    Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase (2004), Oncogene, 23, 30-38.
    View publication on PubMed

Application

Application Comment Organism
medicine levels of enzyme correlate with relative levels of radioresistance and resistance to UV(B) treatment Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens existence of a common mechanism underlying radio- and chemoresistance, which is mediated by the enzyme ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
melanoma cell WM35 cell line Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information existence of a common mechanism underlying radio- and chemoresistance, which is mediated by the enzyme Homo sapiens ?
-
?