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Literature summary for 5.3.3.12 extracted from

  • Pennock, J.L.; Behnke, J.M.; Bickle, Q.D.; Devaney, E.; Grencis, R.K.; Isaac, R.E.; Joshua, G.W.; Selkirk, M.E.; Zhang, Y.; Meyer, D.J.
    Rapid purification and characterization of L-dopachrome-methyl ester tautomerase (macrophage-migration-inhibitory factor) from Trichinella spiralis, Trichuris muris and Brugia pahangi (1998), Biochem. J., 335, 495-498.
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine different sensitivity to inhibition by haematin Homo sapiens
medicine different sensitivity to inhibition by haematin Trichinella spiralis
medicine different sensitivity to inhibition by haematin Brugia pahangi
medicine different sensitivity to inhibition by haematin Trichuris muris

Inhibitors

Inhibitors Comment Organism Structure
haematin 50% inhibition at 0.015 mM Brugia pahangi
haematin 50% inhibition at 0.0002 mM Homo sapiens
haematin 50% inhibition at 0.015 mM Trichinella spiralis
haematin 50% inhibition at 0.0026 mM Trichuris muris

Organism

Organism UniProt Comment Textmining
Brugia pahangi
-
 adult
-
Homo sapiens
-
-
-
no activity in Caenorhabditis elegans
-
-
-
no activity in Heligmosomoides polygyrus
-
-
-
no activity in Hymenolepis diminuta
-
-
-
no activity in Nippostrongylus brasiliensis
-
-
-
no activity in Schistosoma haematobium
-
-
-
no activity in Schistosoma japonicum
-
-
-
no activity in Schistosoma mansoni
-
-
-
Trichinella spiralis
-
-
-
Trichuris muris
-
 adult
-

Purification (Commentary)

Purification (Comment) Organism
-
 Trichinella spiralis
-
 Brugia pahangi
-
 Trichuris muris

Source Tissue

Source Tissue Comment Organism Textmining
larva stage 4 Trichinella spiralis
-