Application | Comment | Organism |
---|---|---|
synthesis | synthesis of TDP-D-ravidosamine, necessary for in vitro glycosylation assays. TDP-D-ravidosamine is the anticipated sugar donor substrate of RavGT (the glycosyltransferase that links D-ravidosamine to the polyketide derived backbone defuco-gilvocarcin V). Defuco-gilvocarcin V exhibits superior anticancer/antibacterial activities | Streptomyces ravidus |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Streptomyces ravidus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
19100 | - |
2 * 19100, SDS-PAGE | Streptomyces ravidus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose | Streptomyces ravidus | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces ravidus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Streptomyces ravidus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose | - |
Streptomyces ravidus | ? | - |
? | |
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose | - |
Streptomyces ravidus | ? | no characterization of the product due to its low yield | ? |
Subunits | Comment | Organism |
---|---|---|
dimer | 2 * 19100, SDS-PAGE | Streptomyces ravidus |
Synonyms | Comment | Organism |
---|---|---|
RavIM | - |
Streptomyces ravidus |
TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase | - |
Streptomyces ravidus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Streptomyces ravidus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Streptomyces ravidus |