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Literature summary for 5.3.2.1 extracted from

  • Pirrung, M.C.; Chen, J.; Rowley, E.G.; McPhall, A.T.
    Mechanistic and stereochemical study of phenylpyruvate tautomerase (1993), J. Am. Chem. Soc., 115, 7103-7110.
No PubMed abstract available
Search for more literature for 5.3.2.1

Inhibitors

Inhibitors Comment Organism Structure
(E)-2-Fluoro-p-hydroxycinnamic acid
-
 Sus scrofa
(E)-2-Fluorocinnamic acid
-
 Sus scrofa
(E)-cinnamic acid
-
 Sus scrofa
(E)-p-hydroxycinnamic acid
-
 Sus scrofa
(p-Hydroxybenzylidene)malonate
-
 Sus scrofa
(Z)-2-Fluorocinnamic acid
-
 Sus scrofa
(Z)-cinnamic acid
-
 Sus scrofa
(Z)-Fluoro-p-hydroxycinnamic acid
-
 Sus scrofa
(Z)-p-hydroxycinnamic acid
-
 Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.072
-
 (4-hydroxyphenyl)pyruvate enol-form, kidney Sus scrofa
2.2
-
 (4-hydroxyphenyl)pyruvate keto-form, kidney Sus scrofa
6.1
-
 phenylpyruvate keto-form, kidney Sus scrofa

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Sus scrofa
-
thyroid gland
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(Diiodohydroxyphenyl)pyruvate keto-form Sus scrofa ?
-
 ?
3-(4-hydroxyphenyl)pyruvate keto-form Sus scrofa 2-hydroxy-3-(4-hydroxyphenyl)prop-2-enoate enol-form ?
Phenylpyruvate r Sus scrofa Phenylpyruvate
-
 ?
Phenylpyruvate keto-form Sus scrofa Phenylpyruvate
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.052
-
 (4-hydroxyphenyl)pyruvate enol-form, kidney Sus scrofa
0.45
-
 phenylpyruvate keto-form, kidney Sus scrofa
1.89
-
 (4-hydroxyphenyl)pyruvate keto-form, kidney Sus scrofa