Any feedback?
Literature summary for 5.3.1.9 extracted from
- Cupin-type phosphoglucose isomerases (Cupin-PGIs) constitute a novel metal-dependent PGI family representing a convergent line of PGI evolution (2005), J. Bacteriol., 187, 1621-1631.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 6-phosphogluconate | - |
Archaeoglobus fulgidus |  |
| 6-phosphogluconate | - |
Methanosarcina mazei | |
| 6-phosphogluconate | - |
Salmonella enterica | |
| EDTA | - |
Archaeoglobus fulgidus | |
| EDTA | - |
Methanosarcina mazei | |
| EDTA | - |
Salmonella enterica | |
| EDTA | - |
Sinorhizobium meliloti | |
| erythrose 4-phosphate | - |
Methanosarcina mazei | |
| erythrose 4-phosphate | - |
Sinorhizobium meliloti | |
| sorbitol-6-phosphate | - |
Archaeoglobus fulgidus | |
| sorbitol-6-phosphate | - |
Methanosarcina mazei | |
| sorbitol-6-phosphate | - |
Salmonella enterica | |
| sorbitol-6-phosphate | - |
Sinorhizobium meliloti | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.4 | - |
D-glucose 6-phosphate | pH 7.4, 50°C | Sinorhizobium meliloti | |
| 0.6 | - |
D-fructose 6-phosphate | pH 7.4, 50°C | Archaeoglobus fulgidus | |
| 0.6 | - |
D-glucose 6-phosphate | pH 7.4, 50°C | Archaeoglobus fulgidus | |
| 0.7 | - |
D-fructose 6-phosphate | pH 7.6, 37°C | Methanosarcina mazei | |
| 0.8 | - |
D-fructose 6-phosphate | pH 7.4, 50°C | Sinorhizobium meliloti | |
| 1 | - |
D-glucose 6-phosphate | pH 7.6, 37°C | Methanosarcina mazei | |
| 1 | - |
D-glucose 6-phosphate | pH 7.2, 37°C | Salmonella enterica | |
| 3 | - |
D-fructose 6-phosphate | pH 7.2, 37°C | Salmonella enterica | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 26834 | - |
2 * 26834, calculated, 2 * 32000, SDS-PAGE | Salmonella enterica |
| 27000 | - |
analytical ultracentrifugation | Archaeoglobus fulgidus |
| 27000 | - |
2 * 34684, calculated, 2 * 27000, SDS-PAGE | Sinorhizobium meliloti |
| 27424 | - |
1 * 27424, calculated, 1 * 28000, SDS-PAGE | Archaeoglobus fulgidus |
| 28000 | - |
gel filtration | Archaeoglobus fulgidus |
| 28000 | - |
gel filtration | Methanosarcina mazei |
| 30209 | - |
1 * 30209, calculated, 1 * 28000, SDS-PAGE | Methanosarcina mazei |
| 32000 | - |
2 * 26834, calculated, 2 * 32000, SDS-PAGE | Salmonella enterica |
| 34684 | - |
2 * 34684, calculated, 2 * 27000, SDS-PAGE | Sinorhizobium meliloti |
| 43000 | - |
gel filtration | Sinorhizobium meliloti |
| 67000 | - |
gel filtration | Salmonella enterica |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Archaeoglobus fulgidus | - |
- |
- |
| Methanosarcina mazei | - |
- |
- |
| Salmonella enterica | - |
serovar typhimurium | - |
| Sinorhizobium meliloti | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-fructose 6-phosphate | - |
Sinorhizobium meliloti | D-glucose 6-phosphate | - |
r | |
| D-fructose 6-phosphate | - |
Salmonella enterica | D-glucose 6-phosphate | - |
r | |
| D-fructose 6-phosphate | - |
Archaeoglobus fulgidus | D-glucose 6-phosphate | - |
r | |
| D-fructose 6-phosphate | - |
Methanosarcina mazei | D-glucose 6-phosphate | - |
r | |
| D-glucose 6-phosphate | - |
Sinorhizobium meliloti | D-fructose 6-phosphate | - |
r | |
| D-glucose 6-phosphate | - |
Salmonella enterica | D-fructose 6-phosphate | - |
r | |
| D-glucose 6-phosphate | - |
Archaeoglobus fulgidus | D-fructose 6-phosphate | - |
r | |
| D-glucose 6-phosphate | - |
Methanosarcina mazei | D-fructose 6-phosphate | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 26834, calculated, 2 * 32000, SDS-PAGE | Salmonella enterica |
| dimer | 2 * 34684, calculated, 2 * 27000, SDS-PAGE | Sinorhizobium meliloti |
| monomer | 1 * 27424, calculated, 1 * 28000, SDS-PAGE | Archaeoglobus fulgidus |
| monomer | 1 * 30209, calculated, 1 * 28000, SDS-PAGE | Methanosarcina mazei |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Cupin-PGI | - |
Sinorhizobium meliloti |
| Cupin-PGI | - |
Salmonella enterica |
| Cupin-PGI | - |
Archaeoglobus fulgidus |
| Cupin-PGI | - |
Methanosarcina mazei |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 55 | - |
- |
Salmonella enterica |
| 57 | - |
- |
Sinorhizobium meliloti |
| 57 | - |
- |
Methanosarcina mazei |
| 82 | - |
- |
Archaeoglobus fulgidus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 58 | - |
melting temperature | Sinorhizobium meliloti |
| 64 | - |
melting temperature | Salmonella enterica |
| 97 | - |
melting temperature | Archaeoglobus fulgidus |
| 97 | - |
melting temperature | Methanosarcina mazei |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.2 | - |
- |
Salmonella enterica |
| 7.4 | - |
- |
Sinorhizobium meliloti |
| 7.4 | - |
- |
Archaeoglobus fulgidus |
| 7.6 | - |
- |
Methanosarcina mazei |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.03 | - |
sorbitol-6-phosphate | pH 7.6, 37°C | Methanosarcina mazei | |
| 0.15 | - |
6-phosphogluconate | pH 7.6, 37°C | Methanosarcina mazei | |
| 0.36 | - |
sorbitol-6-phosphate | pH 7.2, 37°C | Salmonella enterica | |
| 0.54 | - |
sorbitol-6-phosphate | pH 7.4, 50°C | Sinorhizobium meliloti | |
| 0.67 | - |
6-phosphogluconate | pH 7.4, 50°C | Archaeoglobus fulgidus | |
| 0.7 | - |
sorbitol-6-phosphate | pH 7.4, 50°C | Archaeoglobus fulgidus | |
| 1.8 | - |
erythrose 4-phosphate | pH 7.4, 50°C | Sinorhizobium meliloti | |
| 1.8 | - |
erythrose 4-phosphate | pH 7.4, 50°C | Methanosarcina mazei | |
| 2 | 10 | EDTA | pH 7.4, 50°C | Sinorhizobium meliloti | |
| 3 | - |
6-phosphogluconate | pH 7.2, 37°C | Salmonella enterica | |
| 97 | - |
EDTA | pH 7.4, 50°C | Archaeoglobus fulgidus | |
| 101 | - |
EDTA | pH 7.6, 37°C | Methanosarcina mazei | |
| 120 | - |
EDTA | pH 7.2, 37°C | Salmonella enterica | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
