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Literature summary for 5.3.1.9 extracted from

  • Mishra, S.; Raz, A.; Murphy, L.J.
    Insulin-like growth factor binding protein-3 interacts with autocrine motility factor/phosphoglucose isomerase (AMF/PGI) and inhibits the AMF/PGI function (2004), Cancer Res., 64, 2516-2522.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
insulin-like growth factor binding protein-3 both glycosylated and unglycosylated, binding and inhibition of enzyme Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Homo sapiens 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
50000
-
x * 50000, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MCF-7 cell
-
Homo sapiens
-
T-47D cell
-
Homo sapiens
-

Subunits

Subunits Comment Organism
? x * 50000, SDS-PAGE Homo sapiens
More interaction of enzyme with insulin-like growth factor binding protein-3, both glycosylated and unglycosylated, results in formation of a complex of 80 kDa and in dose-dependent inhibition of enzyme Homo sapiens