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Literature summary for 5.3.1.9 extracted from
- Glucosephosphate isomerase from Trypanosoma brucei. Cloning and characterization of the gene and analysis of the enzyme (1989), Eur. J. Biochem., 184, 455-464.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Trypanosoma brucei |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 6-phosphogluconate | - |
Geobacillus stearothermophilus |  |
| 6-phosphogluconate | - |
Oryctolagus cuniculus | |
| 6-phosphogluconate | - |
Saccharomyces cerevisiae | |
| 6-phosphogluconate | - |
Trypanosoma brucei | |
| Agaricic acid | - |
Trypanosoma brucei | |
| suramin | no inhibition | Oryctolagus cuniculus | |
| suramin | - |
Saccharomyces cerevisiae | |
| suramin | - |
Trypanosoma brucei | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.048 | - |
fructose 6-phosphate | - |
Geobacillus stearothermophilus | |
| 0.119 | - |
fructose 6-phosphate | - |
Oryctolagus cuniculus | |
| 0.122 | - |
fructose 6-phosphate | - |
Trypanosoma brucei | |
| 0.167 | - |
fructose 6-phosphate | - |
Saccharomyces cerevisiae | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| glycosome | - |
Trypanosoma brucei | 20015 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Trypanosoma brucei | glycolytic enzyme | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Geobacillus stearothermophilus | - |
- |
- |
| Oryctolagus cuniculus | - |
- |
- |
| Saccharomyces cerevisiae | - |
- |
- |
| Trypanosoma brucei | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| muscle | - |
Oryctolagus cuniculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Fructose 6-phosphate | - |
Oryctolagus cuniculus | Glucose 6-phosphate | - |
? | |
| Fructose 6-phosphate | - |
Trypanosoma brucei | Glucose 6-phosphate | - |
? | |
| Glucose 6-phosphate | - |
Geobacillus stearothermophilus | Fructose 6-phosphate | - |
? | |
| additional information | glycolytic enzyme | Trypanosoma brucei | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 9.5 | - |
Saccharomyces cerevisiae |
| 7 | 9.5 | - |
Oryctolagus cuniculus |
| 7 | 9.5 | - |
Trypanosoma brucei |
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