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Literature summary for 5.3.1.4 extracted from
- Engineering of an L-arabinose metabolic pathway in Corynebacterium glutamicum (2008), Appl. Microbiol. Biotechnol., 77, 1053-1062.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | expression of the Escherichia coli genes araA, araB, and araD encoding L-arabinose isomerase, L-ribulokinase, and L-ribulose-5-phosphate 4-epimerase, respectively, in Corynebacterium glutamicum under the control of a constitutive promoter. The recombinant strain is able to grow on mineral salts medium containing L-arabinose as the sole carbon and energy source. Under oxygen deprivation and with L-arabinose as the sole carbon and energy source, carbon flow of the recombinant strain is redirected to produce up to 40, 37, and 11%, respectively, of the theoretical yields of succinic, lactic, and acetic acids. Usinga sugar mixture containing 5% D-glucose and 1% L-arabinose under oxygen deprivation, cells metabolize L-arabinose at a constant rate, resulting in combined organic acids yield based on the amount of sugar mixture consumed after D-glucose depletion of 83% that is comparable to that before D-glucose depletion, 89% | Escherichia coli |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Corynebacterium glutamicum | Escherichia coli |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
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