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Literature summary for 5.3.1.27 extracted from

  • Lessmeier, L.; Pfeifenschneider, J.; Carnicer, M.; Heux, S.; Portais, J.C.; Wendisch, V.F.
    Production of carbon-13-labeled cadaverine by engineered Corynebacterium glutamicum using carbon-13-labeled methanol as co-substrate (2015), Appl. Microbiol. Biotechnol., 99, 10163-10176 .
    View publication on PubMed

Application

Application Comment Organism
synthesis engineering of a strain of Corynebacterium glutamicum, which is able to produce the polyamide building block cadaverine as non-native product, for coutilization of methanol by expression of the gene encoding NAD+-dependent methanol dehydrogenase (Mdh) from Bacillus methanolicus, deletion of the endogenous aldehyde dehydrogenase genes Ald and FadH and expression of genes for hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase of the ribulose monophosphate pathway. Growth with methanol as sole carbon source is not observed, but in vivo activity of the ribulose monophosphate pathway Bacillus subtilis

Organism

Organism UniProt Comment Textmining
Bacillus subtilis P42404
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Bacillus subtilis 168 P42404
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