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Literature summary for 5.1.99.4 extracted from
- alpha-Methylacyl coenzyme A racemase is immunoreactive in extramammary Paget disease (2007), Am. J. Clin. Pathol., 127, 567-571.
Application
| Application | Comment | Organism |
|---|---|---|
| diagnostics | the enzyme is a tool in the diagnosis of morphologically difficult prostatic carcinoma and is used in combination with the basal cell markers p63 and 34betaE12, the enzyme might also be useful in diagnostics of extramammary Paget disease, EMPD | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (2S)-2-methylacyl-CoA | Homo sapiens | - |
(2R)-2-methylacyl-CoA | - |
? |  |
| additional information | Homo sapiens | enzyme expression is increased in extramammary Paget disease, EMPD, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | enzyme expression is increased in extramammary Paget disease, EMPD, in women and men, immunohistochemic detection, overview | Homo sapiens | - |
| prostate gland | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (2S)-2-methylacyl-CoA | - |
Homo sapiens | (2R)-2-methylacyl-CoA | - |
? | |
| additional information | enzyme expression is increased in extramammary Paget disease, EMPD, overview | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| alpha-methylacyl coenzyme A racemase | - |
Homo sapiens |
| AMACR | - |
Homo sapiens |
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