Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ADP | stabilizes the dimeric form of the enzyme | Sus scrofa | |
ATP | stabilizes the dimeric form of the enzyme, inhibits the heterocomplex with renin, prevents inhibition by NEM, inhibits degradation of the enzyme by thermolysin | Sus scrofa | |
dATP | stabilizes the dimeric form of the enzyme | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-ethylmaleimide | NEM, strong inhibitor in absence of ATP at 0.1-0.3 mM, at 5mM inhibition also in presence of ATP | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
monomer, gel filtration | Sus scrofa |
65000 | - |
dimer, gel filtration | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | P17560 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-D-mannosamine | - |
Sus scrofa | N-acetyl-D-glucosamine | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | resistant to protease digestion | Sus scrofa |
Synonyms | Comment | Organism |
---|---|---|
GlcNAc 2-epimerase | - |
Sus scrofa |
N-acyl-D-glucosamine 2-epimerase | - |
Sus scrofa |
N-acylglucosamine 2-epimerase | - |
Sus scrofa |
renin binding protein | - |
Sus scrofa |
RNBP | inhibits activity of renin, forms heterocomplex with renin, high molecular weight renin, HMW | Sus scrofa |