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Literature summary for 5.1.3.7 extracted from

  • Bhatt, V.S.; Guo, C.Y.; Guan, W.; Zhao, G.; Yi, W.; Liu, Z.J.; Wang, P.G.
    Altered architecture of substrate binding region defines the unique specificity of UDP-GalNAc 4-epimerases (2011), Protein Sci., 20, 856-866.
    View publication on PubMedView publication on EuropePMC

Crystallization (Commentary)

Crystallization (Comment) Organism
microbatch under oil method, using 250 mM ammonium sulfate, 100 mM Bis-Tris pH 6.5, (25% w/v) PEG 3350 Plesiomonas shigelloides

Organism

Organism UniProt Comment Textmining
Plesiomonas shigelloides Q7BJX9
-
-
Plesiomonas shigelloides O17 Q7BJX9
-
-

Purification (Commentary)

Purification (Comment) Organism
nickel-Sepharose column chromatography Plesiomonas shigelloides

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-GlcNAc
-
Plesiomonas shigelloides UDP-GalNAc
-
r
UDP-GlcNAc
-
Plesiomonas shigelloides O17 UDP-GalNAc
-
r

Subunits

Subunits Comment Organism
dimer x-ray crystallography Plesiomonas shigelloides

Synonyms

Synonyms Comment Organism
UDP-GalNAc 4-epimerase
-
Plesiomonas shigelloides
UDP-hexose 4-epimerase
-
Plesiomonas shigelloides
WbgU
-
Plesiomonas shigelloides

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Plesiomonas shigelloides
NADH
-
Plesiomonas shigelloides

General Information

General Information Comment Organism
metabolism the enzyme is involved in biosynthetic pathway of the glycan 2-deoxy-L-altruronic acid that is found in the lipopolysaccharide of Pleisomonas shigelloides Plesiomonas shigelloides