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Literature summary for 5.1.3.4 extracted from

  • Wiedemann, B.; Boles, E.
    Codon-optimized bacterial genes improve L-arabinose fermentation in recombinant Saccharomyces cerevisiae (2008), Appl. Environ. Microbiol., 74, 2043-2050.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
synthesis improvement of a bacterial L-arabinose utilization pathway consisting of L-arabinose isomerase from Bacillus licheniformis and L-ribulokinase and L-ribulose-5-phosphate 4-epimerase from Escherichia coli after expression of the corresponding genes in Saccharomyces cerevisiae. After adaptation of codon usage, yeast transformants show strongly improved L-arabinose conversion rates. The ethanol production rate from L-arabinose can be increased more than 2.5fold from 0.014 g ethanol per h and g dry weight to 0.036 g ethanol per h and g dry weight and the ethanol yield can be increased from 0.24 g ethanol per g consumed L-arabinose to 0.39 g ethanol per g consumed L-arabinose Escherichia coli

Cloned(Commentary)

Cloned (Comment) Organism
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Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
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