BRENDA - Enzyme Database show
show all sequences of 5.1.3.3

Purification and properties of aldose 1-epimerase from Aspergillus niger

Kinoshita, S.; Kadota, K.; Taguchi, H.; Biochim. Biophys. Acta 662, 285-290 (1981)

Data extracted from this reference:

Application
Application
Commentary
Organism
analysis
rapid determination of glucose by aldose 1-epimerase
Aspergillus niger
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
50
-
alpha-D-glucose
-
Aspergillus niger
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
130000
-
2 * 130000, SDS-PAGE
Aspergillus niger
260000
-
gel filtration
Aspergillus niger
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Aspergillus niger
-
-
-
Purification (Commentary)
Commentary
Organism
-
Aspergillus niger
Specific Activity [micromol/min/mg]
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
4.6
-
-
Aspergillus niger
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
alpha-D-galactose
105% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
beta-D-galactose
-
-
-
-
alpha-D-glucose
-
2374
Aspergillus niger
beta-D-glucose
-
2374
Aspergillus niger
-
alpha-D-xylose
31% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
beta-D-xylose
-
-
-
-
alpha-L-arabinose
beta-L-arabinose is epimerized at 108% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
beta-L-arabinose
-
-
-
-
beta-D-Cellobiose
15% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
?
-
-
-
-
beta-D-Fructose
135% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
alpha-D-Fructose
-
2374
Aspergillus niger
-
beta-Lactose
10% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
alpha-Lactose
-
2374
Aspergillus niger
-
beta-Maltose
13% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
alpha-Maltose
-
2374
Aspergillus niger
-
Subunits
Subunits
Commentary
Organism
dimer
2 * 130000, SDS-PAGE
Aspergillus niger
Temperature Stability [C]
Temperature Stability Minimum [C]
Temperature Stability Maximum [C]
Commentary
Organism
55
-
30 min, stable below
Aspergillus niger
60
-
30 min, 5% loss of activity
Aspergillus niger
65
-
30 min, 25% loss of activity
Aspergillus niger
75
-
half-life: 6.9 min
Aspergillus niger
Turnover Number [1/s]
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
2600
-
alpha-D-glucose
-
Aspergillus niger
pH Range
pH Minimum
pH Maximum
Commentary
Organism
5
7
-
Aspergillus niger
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
2
-
20C, 24 h, complete loss of activity
Aspergillus niger
3
-
20C, 24 h, 50% loss of activity
Aspergillus niger
5.5
9
20C, 24 h, no inactivation
Aspergillus niger
10.5
-
20C, 24 h, 66% loss of activity
Aspergillus niger
11
-
20C, 24 h, complete loss of activity
Aspergillus niger
Application (protein specific)
Application
Commentary
Organism
analysis
rapid determination of glucose by aldose 1-epimerase
Aspergillus niger
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
50
-
alpha-D-glucose
-
Aspergillus niger
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
130000
-
2 * 130000, SDS-PAGE
Aspergillus niger
260000
-
gel filtration
Aspergillus niger
Purification (Commentary) (protein specific)
Commentary
Organism
-
Aspergillus niger
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
4.6
-
-
Aspergillus niger
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
alpha-D-galactose
105% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
beta-D-galactose
-
-
-
-
alpha-D-glucose
-
2374
Aspergillus niger
beta-D-glucose
-
2374
Aspergillus niger
-
alpha-D-xylose
31% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
beta-D-xylose
-
-
-
-
alpha-L-arabinose
beta-L-arabinose is epimerized at 108% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
beta-L-arabinose
-
-
-
-
beta-D-Cellobiose
15% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
?
-
-
-
-
beta-D-Fructose
135% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
alpha-D-Fructose
-
2374
Aspergillus niger
-
beta-Lactose
10% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
alpha-Lactose
-
2374
Aspergillus niger
-
beta-Maltose
13% of the activity relative to alpha-D-glucose
2374
Aspergillus niger
alpha-Maltose
-
2374
Aspergillus niger
-
Subunits (protein specific)
Subunits
Commentary
Organism
dimer
2 * 130000, SDS-PAGE
Aspergillus niger
Temperature Stability [C] (protein specific)
Temperature Stability Minimum [C]
Temperature Stability Maximum [C]
Commentary
Organism
55
-
30 min, stable below
Aspergillus niger
60
-
30 min, 5% loss of activity
Aspergillus niger
65
-
30 min, 25% loss of activity
Aspergillus niger
75
-
half-life: 6.9 min
Aspergillus niger
Turnover Number [1/s] (protein specific)
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
2600
-
alpha-D-glucose
-
Aspergillus niger
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
5
7
-
Aspergillus niger
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
2
-
20C, 24 h, complete loss of activity
Aspergillus niger
3
-
20C, 24 h, 50% loss of activity
Aspergillus niger
5.5
9
20C, 24 h, no inactivation
Aspergillus niger
10.5
-
20C, 24 h, 66% loss of activity
Aspergillus niger
11
-
20C, 24 h, complete loss of activity
Aspergillus niger
Other publictions for EC 5.1.3.3
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
747879
Sheshukova
The intergenic interplay betw ...
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728233
Csiszovszki
Structure and function of the ...
Yersinia pestis, Yersinia pestis KIM D27
mBio
2
00053-00011
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728838
Rasul
-
Aldose-l-epimerase: isolation ...
Bos taurus
World Appl. Sci. J.
13
1620-1623
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713653
You
Crystallization and preliminar ...
Escherichia coli
Acta Crystallogr. Sect. F
66
951-953
2010
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684574
Wiedemann
Codon-optimized bacterial gene ...
Bacillus licheniformis
Appl. Environ. Microbiol.
74
2043-2050
2008
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693504
Chiriac
-
Stereoselective synthesis of L ...
Escherichia coli
J. Labelled Compd. Radiopharm.
51
171-174
2008
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693972
Soldatkin
-
Novel sucrose three-enzyme con ...
Sus scrofa
Mater. Sci. Eng. C
28
959-964
2008
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1
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694901
Fekete
Lack of aldose 1-epimerase in ...
Saccharomyces cerevisiae, Trichoderma reesei
Proc. Natl. Acad. Sci. USA
105
7141-7146
2008
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1
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5
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671057
Chittori
Structure of the putative muta ...
Salmonella enterica, Salmonella enterica subsp. enterica serovar Typhimurium, Salmonella enterica subsp. enterica serovar Typhimurium LT2
Acta Crystallogr. Sect. D
63
197-205
2007
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673761
Scott
Characterization of the Saccha ...
Saccharomyces cerevisiae
FEMS Yeast Res.
7
366-371
2007
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661673
Villalobo
Entamoeba histolytica: molecul ...
Entamoeba histolytica
Exp. Parasitol.
110
298-302
2005
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662372
Thoden
The molecular architecture of ...
Saccharomyces cerevisiae
J. Biol. Chem.
280
21900-21907
2005
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651176
Majumdar
UDPgalactose 4-epimerase from ...
Saccharomyces cerevisiae
Eur. J. Biochem.
271
753-759
2004
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660749
Barrett
Heterologous expression of lac ...
Lactococcus lactis
Appl. Environ. Microbiol.
70
2861-2866
2004
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661785
Vilfan
Characterisation and expressio ...
Rhizopus stolonifer
FEMS Microbiol. Lett.
235
101-108
2004
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662224
Thoden
Molecular structure of human g ...
Homo sapiens
J. Biol. Chem.
279
23431-23437
2004
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651324
Timson
Identification and characteris ...
Homo sapiens
FEBS Lett.
543
21-24
2003
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661071
Beebe
Galactose mutarotase: pH depen ...
Escherichia coli
Biochemistry
42
4414-4420
2003
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663325
Thoden
The catalytic mechanism of gal ...
Lactococcus lactis
Protein Sci.
12
1051-1059
2003
-
-
-
1
6
-
-
13
-
-
-
-
-
2
-
-
-
1
-
-
-
-
4
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
-
1
6
-
-
-
-
13
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
16
-
-
-
-
-
-
-
-
-
-
662113
Thoden
High resolution X-ray structur ...
Lactococcus lactis
J. Biol. Chem.
277
20854-20861
2002
-
-
1
1
-
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
662120
Thoden
Structural and kinetic studies ...
Lactococcus lactis
J. Biol. Chem.
277
45458-45465
2002
-
-
-
1
-
-
-
6
-
-
-
-
-
2
-
-
-
-
-
-
-
-
6
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
661052
Beebe
Galactose mutarotase: purifica ...
Escherichia coli
Biochemistry
37
14989-14997
1998
-
-
-
-
2
-
1
2
-
1
-
-
-
2
-
-
-
1
-
-
-
-
1
-
-
-
1
2
-
-
-
1
-
-
-
-
-
-
1
-
2
-
-
1
-
2
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
2
-
-
-
-
-
-
-
-
-
-
2381
Bouffard
Dependence of lactose metaboli ...
Escherichia coli
J. Mol. Biol.
244
269-278
1994
-
-
-
-
-
-
-
-
1
-
-
-
-
3
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2380
Taguchi
Effects of 1,5-anhydro-D-fruct ...
Sus scrofa
Biotechnol. Appl. Biochem.
18
275-283
1993
-
-
-
-
-
-
2
-
-
-
-
-
-
5
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2382
Nakamura
Structure determination of N-t ...
Sus scrofa
Biosci. Biotechnol. Biochem.
57
1772-1774
1993
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2378
Rygus
Inducible high-level expressio ...
Acinetobacter calcoaceticus
Appl. Microbiol. Biotechnol.
35
594-599
1991
-
-
1
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2353
Poolman
Carbohydrate utilization in St ...
Streptococcus thermophilus
J. Bacteriol.
172
4037-4047
1990
-
-
1
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2379
Kuchel
Mutarotase equilibrium exchang ...
Sus scrofa
Biophys. Chem.
32
89-95
1988
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2361
Gatz
Cloning and expression of the ...
Acinetobacter calcoaceticus
J. Bacteriol.
168
31-39
1986
-
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
1
-
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2376
Toyoda
Multiple forms of mutarotases ...
Rattus norvegicus
J. Biochem.
94
421-431
1983
-
-
-
-
-
-
-
19
1
-
3
-
-
2
-
-
1
-
-
6
7
-
5
1
1
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
19
1
-
3
-
-
-
-
1
-
6
7
-
5
1
1
-
1
-
1
-
-
-
-
-
-
-
-
-
2375
Toyoda
Purification and characterizat ...
Sus scrofa
J. Biochem.
91
1889-1898
1982
-
-
-
-
-
-
-
1
-
-
5
-
-
1
-
-
1
-
-
1
1
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
5
-
-
-
-
1
-
1
1
-
1
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
2374
Kinoshita
Purification and properties of ...
Aspergillus niger
Biochim. Biophys. Acta
662
285-290
1981
-
1
-
-
-
-
-
1
-
-
2
-
-
2
-
-
1
-
-
-
1
-
8
1
-
-
4
1
-
1
5
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
1
-
-
1
-
8
1
-
-
4
1
-
1
5
-
-
-
-
-
-
-
2373
Baba
The localization of mutarotase ...
Rattus norvegicus
Experientia
35
1094-1097
1979
-
-
-
-
-
-
-
-
3
-
-
1
-
2
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2372
Chang
Immobilization and characteriz ...
Bos taurus, Sus scrofa
Biotechnol. Bioeng.
19
923-928
1977
-
-
-
-
-
1
-
1
-
-
-
-
-
2
-
-
1
-
-
2
-
-
2
-
1
1
2
-
1
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
-
-
-
1
-
2
-
-
2
-
1
1
2
-
1
1
-
-
-
-
-
-
-
-
2371
Weibel
A coupled enzyme assay for ald ...
Sus scrofa
Anal. Biochem.
70
489-494
1976
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2369
Bailey
Mutarotase (aldose 1-epimerase ...
Bos taurus, Capsicum frutescens, Catfish, Escherichia coli, Gallus gallus, Homo sapiens, Mushroom, Oryctolagus cuniculus, Ovis aries, Rana catesbeiana
Methods Enzymol.
41
471-484
1975
-
-
-
1
-
-
42
7
-
-
10
-
-
10
-
-
1
-
-
5
1
1
19
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
42
-
7
-
-
10
-
-
-
-
1
-
5
1
1
19
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
2370
Fishman
Mutarotase from higher plants ...
Capsicum frutescens
Methods Enzymol.
41
484-487
1975
-
-
-
-
-
-
12
-
-
-
1
-
-
2
-
-
1
-
-
-
-
-
4
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
12
-
-
-
-
1
-
-
-
-
1
-
-
-
-
4
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
2368
Gernert
Mutarotase (aldose-1-epimerase ...
Sus scrofa
Arch. Biochem. Biophys.
161
420-425
1974
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
2365
Fishman
Analysis of a crystalline muta ...
Bos taurus
Biochemistry
12
2490-2495
1973
-
-
-
1
-
-
12
-
-
-
1
-
-
2
-
-
1
-
-
2
-
-
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
12
-
-
-
-
1
-
-
-
-
1
-
2
-
-
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
2366
Fishman
Studies on mutarotase: photoox ...
Bos taurus
Biochemistry
12
2540-2544
1973
-
-
-
-
-
1
4
-
-
-
-
-
-
1
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
4
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2367
Mulhern
Physical characteristics and c ...
Batrachoididae gen. sp., Bos taurus, Canis lupus familiaris, Capsicum frutescens, Catfish, Cavia porcellus, Escherichia coli, Gallus gallus, Homo sapiens, Meriones unguiculatus, Mushroom, Mus musculus, Oryctolagus cuniculus, Ovis aries, Perca flavescens, Rana catesbeiana, Sus scrofa
J. Biol. Chem.
248
4163-4173
1973
-
-
-
-
-
-
8
15
-
-
12
-
-
17
-
-
-
-
-
10
-
-
17
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
15
-
-
12
-
-
-
-
-
-
10
-
-
17
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2364
Hucho
The enzymatically catalyzed mu ...
Escherichia coli
Eur. J. Biochem.
23
489-496
1971
-
-
-
-
-
-
5
5
-
-
-
-
-
3
-
-
-
1
-
-
-
-
4
-
-
-
1
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
5
-
5
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
1
1
-
-
1
-
-
-
-
-
-
-
2362
Bentley
Mutarotase from Penicillium no ...
Penicillium chrysogenum
J. Biol. Chem.
235
1219-1224
1960
-
-
-
-
-
-
1
-
-
-
1
-
-
2
-
-
1
-
-
1
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
1
-
1
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2363
Bentley
Mutarotase from Penicillium no ...
Penicillium chrysogenum
J. Biol. Chem.
235
1225-1232
1960
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-