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Literature summary for 5.1.3.25 extracted from
- A new route to dTDP-6-deoxy-L-talose and dTDP-L-rhamnose: dTDP-L-rhamnose 4-epimerase in Burkholderia thailandensis (2011), Bioorg. Med. Chem. Lett., 21, 3914-3917.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene BTH_I1476, DNA and amino acid sequence determination and analysis | Burkholderia thailandensis |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0247 | - |
dTDP-6-deoxy-beta-L-talose | pH 8.2, temperature not specified in the publication | Burkholderia thailandensis |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dTDP-6-deoxy-beta-L-talose | Burkholderia thailandensis | - |
dTDP-beta-L-rhamnose | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Burkholderia thailandensis | Q2SYH7 | gene BTH_I1476 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dTDP-6-deoxy-beta-L-talose | - |
Burkholderia thailandensis | dTDP-beta-L-rhamnose | - |
r | |
| dTDP-6-deoxy-beta-L-talose | the equilibrium of WibBBth catalysis favors dTDP-beta-L-rhamnose formation | Burkholderia thailandensis | dTDP-beta-L-rhamnose | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| dTDP-6-deoxysugar 4-epimerase | - |
Burkholderia thailandensis |
| dTDP-L-rhamnose 4-epimerase | - |
Burkholderia thailandensis |
| dTDP-Rha 4-epimerase | - |
Burkholderia thailandensis |
| wbiB | - |
Burkholderia thailandensis |
Turnover Number [1/s]
| Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.9 | - |
dTDP-6-deoxy-beta-L-talose | pH 8.2, temperature not specified in the publication | Burkholderia thailandensis | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.8 | 8.4 | in phosphate buffer | Burkholderia thailandensis |
kcat/KM [mM/s]
| kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 36.4 | - |
dTDP-6-deoxy-beta-L-talose | pH 8.2, temperature not specified in the publication | Burkholderia thailandensis | |
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