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Literature summary for 5.1.3.2 extracted from

  • Singh, V.; Satheesh, S.V.; Raghavendra, M.L.; Sadhale, P.P.
    The key enzyme in galactose metabolism, UDP-galactose-4-epimerase, affects cell-wall integrity and morphology in Candida albicans even in the absence of galactose (2007), Fungal Genet. Biol., 44, 563-574.
    View publication on PubMed
Search for more literature for 5.1.3.2

Application

Application Comment Organism
medicine The absence of CaGAL10 alone does not significantly reduce virulence in mouse model studies, but since it leads to increased drug sensitivity, it can be explored as a potential drug target in combination with other candidacidal drugs. Thus the UDP-galactose-4-epimerase plays an important role in the biology of the human pathogen, Candida albicans, like in the case of several other pathogens. Candida albicans

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
75480
-
-
 Candida albicans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-galactose Candida albicans glycolysis and TCA cycle, Leloir pathway UDP-glucose
-
 ?
UDP-galactose Schizosaccharomyces pombe glycolysis and TCA cycle, Leloir pathway UDP-glucose
-
 r

Organism

Organism UniProt Comment Textmining
Candida albicans
-
-
-
Schizosaccharomyces pombe Q9HDU3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-galactose glycolysis and TCA cycle, Leloir pathway Candida albicans UDP-glucose
-
 ?
UDP-galactose glycolysis and TCA cycle, Leloir pathway Schizosaccharomyces pombe UDP-glucose
-
 r

Synonyms

Synonyms Comment Organism
CaGAL10
-
 Candida albicans
GAL10
-
 Candida albicans
UDP-galactose-4-epimerase
-
 Candida albicans
UDP-galactose-4-epimerase
-
 Schizosaccharomyces pombe