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Literature summary for 5.1.3.2 extracted from
- Inhibition and inactivation of bovine mammary and liver UDP-galactose-4-epimerase (1977), J. Biol. Chem., 252, 2089-2094.
General Stability
| General Stability | Organism |
|---|---|
| unstable in absence of mercaptoethanol or dithiothreitol | Bos taurus |
| uridine nucleotides provide almost total protection against the apparent first order inactivation of epimerase by trypsin. NAD+ partially protects against trypsin inactivation | Bos taurus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2-Hydroxy-5-nitrobenzyl bromide | a combination of NAD+ and UDP protects against modification | Bos taurus |  |
| NADH | - |
Bos taurus | |
| NEM | - |
Bos taurus | |
| p-hydroxymercuribenzoate | - |
Bos taurus | |
| Showdomycin | - |
Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Bos taurus | - |
| mammary gland | - |
Bos taurus | - |
| thyroid gland | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-galactose | - |
Bos taurus | UDP-glucose | - |
? | |
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Release 2023.1 (January 2023)
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