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Literature summary for 5.1.3.13 extracted from

  • Graninger, M.; Nidetzky, B.; Heinrichs, D.E.; Whitfield, C.; Messner, P.
    Characterization of dTDP-4-dehydrorhamnose 3,5-epimerase and dTDP-4-dehydrorhamnose reductase, required for dTDP-L-rhamnose biosynthesis in Salmonella enterica serovar typhimurium LT2 (1999), J. Biol. Chem., 274, 25069-25077.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Salmonella enterica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.71
-
 dTDP-6-deoxy-D-xylo-4-hexulose pH 7.0, 25°C Salmonella enterica

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40600
-
 gel filtration Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Salmonella enterica the enzyme is required for dTDP-L-rhamnose biosynthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Salmonella enterica
-
 serovar typhimurium LT2
-

Purification (Commentary)

Purification (Comment) Organism
-
 Salmonella enterica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dTDP-6-deoxy-D-xylo-4-hexulose
-
 Salmonella enterica dTDP-6-deoxy-L-lyxo-4-hexulose
-
 ?
additional information the enzyme is required for dTDP-L-rhamnose biosynthesis Salmonella enterica ?
-
 ?

Subunits

Subunits Comment Organism
dimer
-
 Salmonella enterica

Synonyms

Synonyms Comment Organism
RmlC
-
 Salmonella enterica

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
39
-
 dTDP-6-deoxy-D-xylo-4-hexulose pH 7.0, 25°C Salmonella enterica