Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma dionisii |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma cruzi |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma vivax |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma lewisi |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma conorhini |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma serpentis |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma sp. TCC339 |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma sp. |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma sp. TCC878 |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma cruzi marinkellei |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma erneyi |
DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma grayi |
DNA and amino acid sequence determination and analysis, sequence comparisons and sequence comparisons and phylogenetic analysis, genotyping and genetic organization, detailed overview | Trypanosoma rangeli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
no activity in Trypanosoma brucei | - |
- |
- |
no activity in Trypanosoma congolense | - |
- |
- |
Trypanosoma conorhini | A0A0F6YF18 | - |
- |
Trypanosoma conorhini TCC025 | A0A0F6YF18 | - |
- |
Trypanosoma cruzi | Q4DA80 | proline racemase A | - |
Trypanosoma cruzi | Q868H8 | proline racemase B | - |
Trypanosoma cruzi CL Brener | Q4DA80 | proline racemase A | - |
Trypanosoma cruzi CL Brener | Q868H8 | proline racemase B | - |
Trypanosoma cruzi marinkellei | A0A0F6VXD6 | - |
- |
Trypanosoma cruzi marinkellei TCC344 | A0A0F6VXD6 | - |
- |
Trypanosoma dionisii | - |
- |
- |
Trypanosoma dionisii TCC211 | - |
- |
- |
Trypanosoma erneyi | A0A0F6VXE2 | - |
- |
Trypanosoma erneyi TCC1946 | A0A0F6VXE2 | - |
- |
Trypanosoma grayi | - |
- |
- |
Trypanosoma grayi ANR4 | - |
- |
- |
Trypanosoma lewisi | A0A0F6VXM2 | - |
- |
Trypanosoma lewisi TCC034 | A0A0F6VXM2 | - |
- |
Trypanosoma rangeli | - |
- |
- |
Trypanosoma serpentis | A0A0F6SCP6 | - |
- |
Trypanosoma serpentis TCC1052 | A0A0F6SCP6 | - |
- |
Trypanosoma sp. | A0A0F6VXD9 | - |
- |
Trypanosoma sp. TCC1825 / RCF-2014 | A0A0F6VXD9 | - |
- |
Trypanosoma sp. TCC339 | A0A0F6YER1 | - |
- |
Trypanosoma sp. TCC878 | A0A0F6VXE6 | - |
- |
Trypanosoma sp. TCC878 RCF-2014 | A0A0F6VXE6 | - |
- |
Trypanosoma vivax | B8LFE4 | - |
- |
Trypanosoma vivax Y486 | B8LFE4 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
PA45-A | - |
Trypanosoma cruzi |
PA45-B | - |
Trypanosoma cruzi |
PRAC | - |
Trypanosoma dionisii |
PRAC | - |
Trypanosoma cruzi |
PRAC | - |
Trypanosoma rangeli |
PRAC | - |
Trypanosoma vivax |
PRAC | - |
Trypanosoma lewisi |
PRAC | - |
Trypanosoma conorhini |
PRAC | - |
Trypanosoma serpentis |
PRAC | - |
Trypanosoma sp. TCC339 |
PRAC | - |
Trypanosoma sp. |
PRAC | - |
Trypanosoma sp. TCC878 |
PRAC | - |
Trypanosoma cruzi marinkellei |
PRAC | - |
Trypanosoma erneyi |
PRAC | - |
Trypanosoma grayi |
PRAC1 | - |
Trypanosoma vivax |
proline racemase A | - |
Trypanosoma cruzi |
proline racemase B | - |
Trypanosoma cruzi |
TcPRAC | - |
Trypanosoma cruzi |
Tgr.146.1080 | locus name | Trypanosoma grayi |
TryPRAC | - |
Trypanosoma dionisii |
TryPRAC | - |
Trypanosoma cruzi |
TryPRAC | - |
Trypanosoma rangeli |
TryPRAC | - |
Trypanosoma vivax |
TryPRAC | - |
Trypanosoma lewisi |
TryPRAC | - |
Trypanosoma conorhini |
TryPRAC | - |
Trypanosoma serpentis |
TryPRAC | - |
Trypanosoma sp. TCC339 |
TryPRAC | - |
Trypanosoma sp. |
TryPRAC | - |
Trypanosoma sp. TCC878 |
TryPRAC | - |
Trypanosoma cruzi marinkellei |
TryPRAC | - |
Trypanosoma erneyi |
TryPRAC | - |
Trypanosoma grayi |
TvPRAC | - |
Trypanosoma vivax |
General Information | Comment | Organism |
---|---|---|
evolution | phylogenetic and syntenic data support a single horizontal transfer to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma vivax |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma dionisii |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma cruzi |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma rangeli |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma lewisi |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma conorhini |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma serpentis |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma sp. TCC339 |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma sp. |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma sp. TCC878 |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma cruzi marinkellei |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma erneyi |
evolution | phylogenetic and syntenic data support a single horizontal transference to a Trypanosoma ancestor of a prokaryotic proline racemase implicated in parasite evasion from host defences. TryPRAC homologues as single copy genes per haploid genome in 12 of 15 Trypanosoma species, including Trypanosoma cruzi and Trypanosoma cruzi marinkellei, Trypanosoma dionisii, Trypanosoma erneyi, Trypanosoma rangeli, Trypanosoma conorhini and Trypanosoma lewisi, all parasites of mammals. Polymorphisms in TcPRAC genes match Trypanosoma cruzi genotypes: TcI-TcIV and Tcbat have unique genes, while the hybrids TcV and TcVI contain TcPRACA and TcPRACB from parental TcII and TcIII, respectively. PRAC homologues are identified in trypanosomes from anurans, snakes, crocodiles, lizards, and birds. Most trypanosomes have intact PRAC genes. Trypanosoma rangeli possesses only pseudogenes, maybe in the process of being lost. Trypanosoma brucei, Trypanosoma congolense and their allied species, except the more distantly related Trypanosoma vivax, have completely lost PRAC genes. The genealogy of TryPRAC homologs supports an evolutionary history congruent with the Trypanosoma phylogeny | Trypanosoma grayi |