Cloned (Comment) | Organism |
---|---|
gene murL, shotgun cloning experiment with DGlu auxotrophic Escherichia coli strain WM335 | Xanthomonas oryzae |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Xanthomonas oryzae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + UDP-MurNAc-L-Ala-L-Glu | Xanthomonas oryzae | - |
AMP + diphosphate + UDP-MurNAc-L-Ala-D-Glu | - |
ir | |
ATP + UDP-MurNAc-L-Ala-L-Glu | Xanthomonas oryzae MAFF311018 | - |
AMP + diphosphate + UDP-MurNAc-L-Ala-D-Glu | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Xanthomonas oryzae | Q5H398 | - |
- |
Xanthomonas oryzae MAFF311018 | Q5H398 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + UDP-MurNAc-L-Ala-L-Glu | - |
Xanthomonas oryzae | AMP + diphosphate + UDP-MurNAc-L-Ala-D-Glu | - |
ir | |
ATP + UDP-MurNAc-L-Ala-L-Glu | the terminal L-Glu of the substrate is converted into D-Glu | Xanthomonas oryzae | AMP + diphosphate + UDP-MurNAc-L-Ala-D-Glu | - |
ir | |
ATP + UDP-MurNAc-L-Ala-L-Glu | - |
Xanthomonas oryzae MAFF311018 | AMP + diphosphate + UDP-MurNAc-L-Ala-D-Glu | - |
ir | |
ATP + UDP-MurNAc-L-Ala-L-Glu | the terminal L-Glu of the substrate is converted into D-Glu | Xanthomonas oryzae MAFF311018 | AMP + diphosphate + UDP-MurNAc-L-Ala-D-Glu | - |
ir | |
additional information | XOO_1319 is a distinct type of glycopeptidyl-glutamate epimerase and is designated XOO_1319 as UDP-MurNAc-LAla-L-Glu epimerase, MurL. It shows no activity in the reverse reaction with UDP-MurNAc-L-Ala-D-Glu. MurL requires ATP and Mg2+ for its activity and AMP is generated as a side product, suggesting that the substrate is activated by adenylation | Xanthomonas oryzae | ? | - |
? | |
additional information | XOO_1319 is a distinct type of glycopeptidyl-glutamate epimerase and is designated XOO_1319 as UDP-MurNAc-LAla-L-Glu epimerase, MurL. It shows no activity in the reverse reaction with UDP-MurNAc-L-Ala-D-Glu. MurL requires ATP and Mg2+ for its activity and AMP is generated as a side product, suggesting that the substrate is activated by adenylation | Xanthomonas oryzae MAFF311018 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MurL | - |
Xanthomonas oryzae |
UDP-MurNAc-L-Ala-L-Glu epimerase | - |
Xanthomonas oryzae |
XOO_1319 | - |
Xanthomonas oryzae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Xanthomonas oryzae |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the biosynthesis of UDP-MurNAc-pentapeptide, pathway overview | Xanthomonas oryzae |
additional information | MurL lacks known conserved domains and cofactor binding domains | Xanthomonas oryzae |