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Literature summary for 5.1.1.18 extracted from

  • Dun, Y.; Mysona, B.; Itagaki, S.; Martin-Studdard, A.; Ganapathy, V.; Smith, S.B.
    Functional and molecular analysis of D-serine transport in retinal Mueller cells (2007), Exp. Eye Res., 84, 191-199.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 5.1.1.18

Cloned(Commentary)

Cloned (Comment) Organism
total RNA is isolated from rMC-1 cells reverse-transcribed into cDNA and subjected to PCR using rat-specific SR primers, expression analysis of the enzyme in retinal Mueller cells Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38000
-
 x * 38000, SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-serine Rattus norvegicus D-serine, an endogenous co-agonist of N-methyl-D-aspartate receptors in vertebrate retina, modulates glutamate sensitivity of retinal neurons, overview D-serine
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q76EQ0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
eye
-
 Rattus norvegicus
-
retina
-
 Rattus norvegicus
-
rMC-1 cell a retinal Mueller cell line, enzyme expression analysis, uptake of D-serine in Mueller cells is specific for neutral amino acids and excludes anionic and cationic amino acids, specificity and activity of transporters, overview Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-serine
-
 Rattus norvegicus D-serine
-
 ?
L-serine D-serine, an endogenous co-agonist of N-methyl-D-aspartate receptors in vertebrate retina, modulates glutamate sensitivity of retinal neurons, overview Rattus norvegicus D-serine
-
 ?

Subunits

Subunits Comment Organism
? x * 38000, SDS-PAGE Rattus norvegicus