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Literature summary for 5.1.1.1 extracted from

  • Hoffmann, K.; Schneider-Scherzer, E.; Kleinkauf, H.; Zocher, R.
    Purification and characterization of eucaryotic alanine racemase acting as key enzyme in cyclosporin biosynthesis (1994), J. Biol. Chem., 269, 12710-12714.
    View publication on PubMed
Search for more literature for 5.1.1.1

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2
-
 D-Ala
-
 Tolypocladium inflatum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
 3 or 4 * 37000, SDS-PAGE Tolypocladium inflatum
120000 150000 gel filtration Tolypocladium inflatum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Tolypocladium inflatum key enzyme in cyclosporin A biosynthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Tolypocladium inflatum
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Tolypocladium inflatum

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
143
-
-
 Tolypocladium inflatum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Ala
-
 Tolypocladium inflatum D-Ala
-
 ?
additional information key enzyme in cyclosporin A biosynthesis Tolypocladium inflatum ?
-
 ?

Subunits

Subunits Comment Organism
? 3 or 4 * 37000, SDS-PAGE Tolypocladium inflatum

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
42
-
 L-Ala Tolypocladium inflatum

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.8
-
 L-Ala Tolypocladium inflatum
9.5
-
 D-Ala Tolypocladium inflatum

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate required as coenzyme Tolypocladium inflatum