Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P77072 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
RHg+ + H+ | - |
Escherichia coli | RH + Hg2+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
merB | - |
Escherichia coli |
organomercurial lyase | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
additional information | quantum chemical calculations have been performed to compare the two chief candidate mechanisms for the Hg-C protonolysis catalyzed by the organomercurial lyase, MerB. The coordination of R-Hg(II) by two cysteine thiolates is necessary and sufficient to activate the Hg-C bond toward protonolysis. | Escherichia coli |