Literature summary for 4.98.1.1 extracted from

Armas, A.; Balparda, M.; Terenzi, A.; Busi, M.; Pagani, M.; Gomez-Casati, D.
Ferrochelatase activity of plant frataxin (2019), Biochimie, 156, 118-122 .

Search for more literature for 4.98.1.1

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Arabidopsis thaliana	5739	-

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	Q9ZR07	cf. EC 1.16.3.1	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
3.08	-	pH 8.0, 25°C	Arabidopsis thaliana
4.8	-	presence of cysteine desulfurase NFS1 and small mitochondrial protein ISD11, pH 8.0, 25°C	Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
protoporphyrin IX + Fe2+	-	Arabidopsis thaliana	protoheme + 2 H+	-	?

Synonyms

Synonyms	Comment	Organism
frataxin	-	Arabidopsis thaliana

General Information

General Information	Comment	Organism
physiological function	frataxin catalyzes the formation of heme in vitro when it is incubated with iron and protoporphyrin IX. In combination with cysteine desulfurase NFS1 and small mitochondrial protein ISD11 the ferrochelatase activity is increased	Arabidopsis thaliana

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Release 2023.1 (January 2023)