Application | Comment | Organism |
---|---|---|
medicine | photodynamic therapy (PDT) for tumors is based on the tumor-selective accumulation of a photosensitizer, protoporphyrin IX (PpIX), followed by irradiation with visible light, PpIX accumulation in 5-aminolevulinic acid, treated U937 cells is increased by the inhibition of ferrochelatase | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
deferoxamine | - |
Homo sapiens | |
Mn2+ | - |
Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
protoporphyrin IX + Fe2+ | Homo sapiens | - |
protoheme IX + 2 H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
protoporphyrin IX + Fe2+ | - |
Homo sapiens | protoheme IX + 2 H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ferrochelatase | - |
Homo sapiens |