Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.98.1.1 extracted from

  • Jacobs, J.M.; Sinclair, P.R.; Sinclair, J.F.; Gorman, N.; Walton, H.S.; Wood, S.G.; Nichols, C.
    Formation of zinc protoporphyrin in cultured hepatocytes: effects of ferrochelatase inhibition, iron chelation or lead (1998), Toxicology, 125, 95-105.
    View publication on PubMed
Search for more literature for 4.98.1.1

Inhibitors

Inhibitors Comment Organism Structure
2,2'-dipyridyl
-
 Rattus norvegicus
N-methylmesoporphyrin
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protoporphyrin IX + Fe2+ Gallus gallus final step of heme biosynthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte embryonal, cultured Gallus gallus
-
hepatocyte embryonal, cultured Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protoporphyrin + Fe2+
-
 Gallus gallus protoheme + 2 H+
-
 ?
protoporphyrin + Fe2+
-
 Rattus norvegicus protoheme + 2 H+
-
 ?
protoporphyrin + Zn2+
-
 Rattus norvegicus Zn2+-protoporphyrin + H+
-
 ?
protoporphyrin IX + Fe2+ final step of heme biosynthesis Gallus gallus ?
-
 ?