Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.98.1.1 extracted from

  • Dailey, H.A.; Fleming, J.E.
    Bovine ferrochelatase. Kinetic analysis of inhibition by N-methylprotoporphyrin, manganese, and heme (1983), J. Biol. Chem., 258, 11453-11459.
    View publication on PubMed
Search for more literature for 4.98.1.1

Inhibitors

Inhibitors Comment Organism Structure
heme
-
 Bos taurus
Hg2+
-
 Bos taurus
Mn2+
-
 Bos taurus
N-Methylprotoporphyrin
-
 Bos taurus
Pb2+
-
 Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Bos taurus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
 1 * 40000, SDS-PAGE, gel chromatography in presence of sodium cholate Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protoporphyrin IX + Fe2+ Bos taurus final step of heme biosynthesis ?
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deuteroporphyrin + Fe2+
-
 Bos taurus deuteroheme + 2 H+
-
 ?
mesoporphyrin + Fe2+
-
 Bos taurus mesoheme + H+
-
 ?
additional information 2,4-disulfonic deuteroporphyrin, 2,4-bisglycol deuteroporphyrin Bos taurus ?
-
 ?
protoporphyrin + Fe2+
-
 Bos taurus protoheme + 2 H+
-
 ?
protoporphyrin IX + Fe2+ final step of heme biosynthesis Bos taurus ?
-
 ?

Subunits

Subunits Comment Organism
? 1 * 40000, SDS-PAGE, gel chromatography in presence of sodium cholate Bos taurus