Literature summary for 4.6.1.24 extracted from

Dubey, S.; Kalia, Y.N.
Electrically-assisted delivery of an anionic protein across intact skin: cathodal iontophoresis of biologically active ribonuclease T1 (2011), J. Control. Release, 152, 356-362.

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Organism

Organism	UniProt	Comment	Textmining
Aspergillus oryzae	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
commercial preparation	-	Aspergillus oryzae	-

Synonyms

Synonyms	Comment	Organism
RNase T1	-	Aspergillus oryzae

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.4	-	assay at	Aspergillus oryzae

General Information

General Information	Comment	Organism
additional information	analysis of cumulative permeation and skin deposition of negatively charged RNAse T1 using porcine ear skin. RNAse T1 permeation is dependent upon current density,while skin deposition is not. RNAse T1 retains structural integrity and enzymatic function postiontophoresis. RNAse T1 appears to be bound to the epidermis alone	Aspergillus oryzae

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Release 2023.1 (January 2023)