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Literature summary for 4.6.1.2 extracted from
- Population pharmacokinetics and pharmacodynamics of cinaciguat, a soluble guanylate cyclase activator, in patients with acute decompensated heart failure (2010), Clin. Pharmacokinet., 49, 119-129.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| BAY 58-2667 | cinaciguat, a soluble guanylate cyclase activator | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP | Homo sapiens | - |
3',5'-cyclic-GMP + diphosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP | - |
Homo sapiens | 3',5'-cyclic-GMP + diphosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| sGC | - |
Homo sapiens |
| soluble guanylyl cyclase | - |
Homo sapiens |
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