Cloned (Comment) | Organism |
---|---|
gene encoding isozyme Gyc-89Da, expression analysis and promoter analysis, expression in Saccharomces cerevisiae | Drosophila melanogaster |
gene encoding isozyme Gyc-89Db, expression analysis and promoter analysis, expression in Saccharomces cerevisiae | Drosophila melanogaster |
Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of an isozyme Gyc-89Da deficient mutant, reduced levels of cGMP in Gyc-89Da neurons have no effect on larval ecdysis or eclosion, but isozyme expression is necessary early in adult development to prevent eclosion, phenotype, overview | Drosophila melanogaster |
additional information | generation of an isozyme Gyc-89Db deficient mutant, reduced levels of cGMP in Gyc-89Db neurons have no effect on larval ecdysis or eclosion, but isozyme expression is necessary early in adult development to prevent eclosion, phenotype, overview | Drosophila melanogaster |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tetanus toxin | expression of tetanus toxin in the neurons, that express isozyme Gyc-89Da, blocks their synaptic activity; expression of tetanus toxin in the neurons, that express isozyme Gyc-89Db, blocks their synaptic activity | Drosophila melanogaster |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
synapse | - |
Drosophila melanogaster | 45202 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | Drosophila melanogaster | isozyme Gyc-89Da in neurons is necessary early in adult development to prevent eclosion, overview | 3',5'-cyclic GMP + diphosphate | - |
? | |
GTP | Drosophila melanogaster | isozyme Gyc-89Db in neurons is necessary early in adult development to prevent eclosion, overview | 3',5'-cyclic GMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | Q9VEU5 | - |
- |
Drosophila melanogaster | Q9VEU6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
neuron | the isozyme Gyc-89Da is encoded in neurons that are required for larval and adult ecdyses in the fruit fly | Drosophila melanogaster | - |
neuron | the isozyme Gyc-89Db is encoded in neurons that are required for larval and adult ecdyses in the fruit fly | Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | - |
Drosophila melanogaster | 3',5'-cyclic GMP + diphosphate | - |
? | |
GTP | isozyme Gyc-89Da in neurons is necessary early in adult development to prevent eclosion, overview | Drosophila melanogaster | 3',5'-cyclic GMP + diphosphate | - |
? | |
GTP | isozyme Gyc-89Db in neurons is necessary early in adult development to prevent eclosion, overview | Drosophila melanogaster | 3',5'-cyclic GMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Gyc-89Da | - |
Drosophila melanogaster |
Gyc-89Db | - |
Drosophila melanogaster |
soluble guanylyl cyclase | - |
Drosophila melanogaster |