Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | tirofiban, which mimics the structure of arginine-glycine-aspartic acid peptides, up-regulates soluble guanylate cyclase beta1 subunit, sGC-beta1, expression in contractile vascular smooth muscle cells and in aorta from rats, and tirofiban reverses the down-regulation of soluble guanylate cyclase content promoted by chronic treatment with NO donors and NO donor tachyphylaxis | Rattus norvegicus | |
sodium nitroprusside | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
[1,2,4]-oxadiazolo[4,3-a]quinoxalin-1-one | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
soluble | - |
Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | Rattus norvegicus | - |
3',5'-cyclic GMP + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Wistar, Wistar Kyoto, and spontaneously hypertensive rats, isozyme soluble guanylate cyclase beta1, sGC-beta1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
aorta | vascular wall and smooth muscle cells | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP | - |
Rattus norvegicus | 3',5'-cyclic GMP + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
sGC | - |
Rattus norvegicus |
soluble guanylate cyclase | - |
Rattus norvegicus |