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Literature summary for 4.6.1.2 extracted from
- Properties and subcellular distribution of guanylate cyclase activity in rat renal medulla: correlation with tissue content of guanosine 3 ,5 -monophosphate (1976), Biochemistry, 15, 5131-5137.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| phenylhydrazine | acivation | Rattus norvegicus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | 1-2 mM | Rattus norvegicus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.11 | - |
GTP | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| particle-bound | - |
Rattus norvegicus | - |
- |
| soluble | - |
Rattus norvegicus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | activation of soluble enzyme | Rattus norvegicus | |
| Ca2+ | activation at 0.05 mM | Rattus norvegicus | |
| Mn2+ | - |
Rattus norvegicus | |
| NaN3 | activation | Rattus norvegicus | |
| NaNO3 | activation | Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| renal medulla | - |
Rattus norvegicus | - |
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