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Literature summary for 4.6.1.19 extracted from

  • Subbarayan, P.R.; Deutscher, M.P.
    Escherichia coli RNase M is a multiply altered form of RNase I (2001), RNA, 7, 1702-1707.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
rna gene encoding the enzyme contains a UGA nonsense codon at position 5 and is a multiply altered form of RNase I gene Escherichia coli

Protein Variants

Protein Variants Comment Organism
additional information alteration of the RNase I by mutantion of 3 amino acids to RNase M sequence and confer of enzyme properties, comparison of RNase M mutant strain activities Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RNA + H2O Escherichia coli enzyme is responsible for degradation of mRNA ?
-
?
RNA + H2O Escherichia coli CA265 enzyme is responsible for degradation of mRNA ?
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
rna gene
-
Escherichia coli CA265
-
rna gene
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
RNA + H2O enzyme is responsible for degradation of mRNA Escherichia coli ?
-
?
RNA + H2O enzyme is responsible for degradation of mRNA Escherichia coli CA265 ?
-
?
RNA + H2O 5S rRNA and tRNA from Escherichia coli Escherichia coli nucleoside 3'-phosphates + 3'-phosphooligonucleotides
-
?
RNA + H2O 5S rRNA and tRNA from Escherichia coli Escherichia coli CA265 nucleoside 3'-phosphates + 3'-phosphooligonucleotides
-
?

Synonyms

Synonyms Comment Organism
More enzyme is a multiply altered form of RNase I Escherichia coli
RNase M
-
Escherichia coli

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Escherichia coli

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Escherichia coli