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Literature summary for 4.6.1.19 extracted from

  • Naskalski, J.; Anyszek, T.; Surdacka, E.; Hoyer, B.; Sulowicz, W.
    Acid ribonuclease and alkaline ribonuclease isoenzymes in plasma of patients with decreased glomerular filtration rate (2004), Clin. Chem. Lab. Med., 42, 279-282.
    View publication on PubMed
Search for more literature for 4.6.1.19

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens enzyme concentration in plasma is increased in case of impaired glomerular filtration rate of the kidney, patients suffering chronic renal insufficiency accumulate the enzyme in the plasma low molecular weight fraction ?
-
 ?
RNA + H2O Homo sapiens degradation of RNA ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
 Homo sapiens
-
leukocyte the plasma acid RNase is mainly of leukocyte origin Homo sapiens
-
plasma
-
 Homo sapiens
-
serum
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 enzyme levels at different kidney glomerular filtration rates of blood Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme concentration in plasma is increased in case of impaired glomerular filtration rate of the kidney, patients suffering chronic renal insufficiency accumulate the enzyme in the plasma low molecular weight fraction Homo sapiens ?
-
 ?
RNA + H2O degradation of RNA Homo sapiens ?
-
 ?
RNA + H2O yeast RNA Homo sapiens ?
-
 ?

Subunits

Subunits Comment Organism
? x * 15000-16000 Homo sapiens

Synonyms

Synonyms Comment Organism
acid RNase
-
 Homo sapiens
leukocytic-type acid RNase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
 assay at Homo sapiens

pI Value

Organism Comment pI Value Maximum pI Value
Homo sapiens above
-
 10