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Literature summary for 4.6.1.18 extracted from
- Increased N-glycosylation of Asn(88) in serum pancreatic ribonuclease 1 is a novel diagnostic marker for pancreatic cancer (2014), Sci. Rep., 4, 6715.
Application
| Application | Comment | Organism |
|---|---|---|
| diagnostics | increased N-glycosylation of Asn88 in serum pancreatic ribonuclease 1 is a diagnostic marker for pancreatic cancer. Development of an assay to specifically detect unglycosylated Asn88 in denatured RNase1, overview | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of wild-type and mutant enzymes in CHO-K1 cells | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Homo sapiens | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | N-glycosylation of Asn88 in serum pancreatic ribonuclease 1 is specifically increased in pancreatic cancer patients and blocks binding of specific antibodies, RrhRN0723 mAb and mAb RN15013, to the enzyme. Development of an assay to specifically detect unglycosylated Asn88 in denatured RNase1, overview | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| commercial preparation | MGC cDNA clone | Homo sapiens | - |
| serum | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| pancreatic ribonuclease 1 | - |
Homo sapiens |
| RNase1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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